Ultrasonographic changes of submandibular glands in irradiated patients for head and neck cancers
نویسندگان
چکیده مقاله:
Background: Salivary glands (SGs) are usually irradiated during radiotherapy for head and neck cancers, which may lead to radiation-induced changes. These changes could be evaluated safely by ultrasonography; however, there have been few studies in this regard. Thus, we aimed to investigate the changes in post-radiotherapy submandibular glands using ultrasonography in patients undergoing head-neck radiotherapy. Materials and Methods: We evaluated 46 submandibular glands of 23 patients ultrasonographically in terms of echogenicity, echotexture, margin, and dimensional (anteroposterior, superoinferior, mediolateral length and volume) changes before radiotherapy, and at the second and sixth months after radiotherapy. Results: About 93.5% of the submandibular glands were hyperechoic before RT. When the same submandibular glands were evaluated two months later, 39.1% were hyperechoic. Six months after the therapy, 56,5% were hyperechoic (p<0.001). There is also a similar trend for the echotexture (p<0.001) and the regularity margins before RT, two months after-, and at sixth month after RT (p<0.001). Also, there were statistically significant differences between anteroposterior, superoinferior, mediolateral lengths, and volumetric values measured before radiotherapy and at the end of two and six months after radiotherapy onset (p<0.001). Conclusion: We revealed that submandibular glands were isoechoic or hypoechoic, heterogeneous, and irregular after radiotherapy; however, as the time elapsed after radiotherapy, the parenchyma structure returned to normal in half of them. Indeed, defining radiotherapy-related changes in SGs may be helpful in better understanding the mechanism of common oral complications associated with RT, and in the differential diagnosis of other SG diseases.
منابع مشابه
Effect of cryotherapy on oral mucositis in patients with head and neck cancers receiving radiotherapy
Background: Mucositis is an important adverse effect of cancer treatment. The aim of this study was to investigate the effect of ice cubes on oral mucositis following head and neck radiotherapy. Materials and Methods: A randomized controlled trial was conducted on 40 head and neck cancer patients who underwent radiotherapy. The patients were randomly divided into two experimental and control gr...
متن کاملPositional changes in parotid glands during head and neck radiation therapy
Introduction: Xerostomia is the most common complication due to radiation–induced damage to salivary glands in head and neck cancer radiotherapy and it reduces quality of life. Parotid glands are main glands which they are account for secretion of stimulated saliva. Studies have demonstrated that mean tolerance parotid’s radiation dose under 26-30 Gy result in an increase in t...
متن کاملOsteonecrosis in patients irradiated for head and neck carcinoma.
One hundred patients irradiated for cancers of the oral cavity, oropharynx, and nasopharynx were evaluated for the occurrence of osteonecrosis and associated predisposing factors. Selection was based on availability of complete dental records, a minimum of six months follow-up, and treatment fields, which included maxilla and/or mandible. Bone doses were calculated by using radiotherapy treatme...
متن کاملAssessment of the Preventive Effect of Pilocarpine on Radiotherapy-Induced Xerostomia in Patients with Head and Neck Cancers
Introduction Xerostomia is one of side-effects of radiotherapy for head and neck cancers. No definitive method has been proposed for the treatment of this condition. However, pilocarpine is considered effective for the management of chronic xerostomia. The purpose of the present study was to assess the preventive effect of pilocarpine. Materials and Methods This study was performed on 34 patien...
متن کاملEpidemiological aspects of head and neck cancers in a population of south east region of Iran
Introduction: The geographical distribution of head and neck cancer shows considerable variation and it is site dependent. The review of the literature shows few data concerning the head and neck cancer patterns in Iran. The purpose of this study was to represent epidemiological aspects of head and neck cancers in south east of Iran. Materials &Methods: In this retrospective study, from a to...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ذخیره در منابع من قبلا به منابع من ذحیره شده{@ msg_add @}
عنوان ژورنال
دوره 19 شماره 1
صفحات 127- 134
تاریخ انتشار 2021-01
با دنبال کردن یک ژورنال هنگامی که شماره جدید این ژورنال منتشر می شود به شما از طریق ایمیل اطلاع داده می شود.
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023